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| 【主 题】 ： |
Constitutive Knockout |
| 【联系人名】 ： |
Shirley |
| 【电子邮件】 ： |
contact@creative-animodel.com |
| 【联系电话】 ： |
16316269181 |
| 【发布日期】 ： |
2015-1-26 |
| 【详细说明】 ： |
Creative Animodel's high-throughput conventional knockout technology enables us to identify and validate the utility of genomic targets within a living model at an extraordinary scale and speed. With Creative Animodel, you get targeted knockouts generated through proven technologies and comprehensive phenotypic data analyzed across consistent protocols.
Steps
1 : Subcloning and characterization of the locus of interest
2 : Constitutive knockout vector construction(targeting vector)
3 : Homologous recombination in ES cells
4 : Blastocyst injection and chimera generation
5 : Breeding to the F1 and F2 generation
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English
