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| 【主 题】 ： |
Human Villous Trophoblasts (HVT) |
| 【联系人名】 ： |
Wendy |
| 【电子邮件】 ： |
contact@creative-bioarray.com |
| 【联系电话】 ： |
1-631-626-9181 |
| 【发布日期】 ： |
2015-1-26 |
| 【详细说明】 ： |
The trophoblast begins at the outer covering of the
early blastocyst and provides the route of
nourishment between the maternal endometrium and the
developing embryo. The trophoblast adhesion to the
uterine wall is the requisite first step of
implantation and, subsequently, placentation. Human
villous tryophoblasts (HVT) covering the villi of
the placenta provide the surface for the exchange of
oxygen and nutrient with the maternal circulation.
They synthesize and release chorionic gonadotropin,
placental lactogen and angiogenin ; expression of
CXCR4, CCR5 and prolactin gene family. They acquire
CCR1 as they differentiate to an invasive phenotype
at the villous-anchoring sites. The feature of HVT
together with the recent establishment of
trophoblast stem cells makes them an ideal genetic
platform to study cell differentiation and
organogenesis.HVT from Bioarray Research
Laboratories are isolated from human placental
villi. HVT are cryopreserved at passage primary
culture and delivered frozen. Each vial contains >1
x 10^6 cells in 1 ml volume. HVT are characterized
by immunofluorescent method with antibodies to
alpha-and beta-HCG. HVT are negative for HIV-1, HBV,
HCV, mycoplasma, bacteria, yeast and fungi. HVT are
guaranteed to further culture the condition provided
by Bioarray Research Laboratories.
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English
