|
|
|
| 【主 题】 ： |
Human Villous Mesenchymal Fibroblasts (HVMF) |
| 【联系人名】 ： |
Wendy |
| 【电子邮件】 ： |
contact@creative-bioarray.com |
| 【联系电话】 ： |
1-631-626-9181 |
| 【发布日期】 ： |
2015-1-26 |
| 【详细说明】 ： |
Fibroblasts are mesenchymal cells which are derived
from the embryonic mesoderm. Since tissue-specific
mesenchymal cells are essential for normal organ
development, the villous mesenchymal fibroblasts
(VMF) have been used as a model system for studying
the cellular mechanisms involved in regulating human
placental growth. The VMF lie directly beneath the
villous basement membrane; they synthesize HGF, CSF-
1, granulocyte CSF and IL-6 and play an important
role in the regulation of trophoblast growth and
function. Studies have shown that paracrine
interaction between placental villous mesenchymal
fibroblast and the cytotrophoblast in anchoring
sites is required in stimulating trophoblast
infiltration.HVMF from Bioarray Research
Laboratories are isolated from human placental
villi. HVMF are cryopreserved at primary culture and
delivered frozen. Each vial contains >5 x 10^5 cells
in 1 ml volume. HVMF are characterized by
immunofluorescent method with antibodies to CD90 and
vimentin. HVMF are negative for HIV-1, HBV, HCV,
mycoplasma, bacteria, yeast and fungi. HVMF are
guaranteed to further expand for 15 population
doublings at the conditions provided by Bioarray
Research Laboratories.
|
|
|
|
|
English
