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| 【主 题】 ： |
Recombinant Human Cystatin A (Stefin A) |
| 【联系人名】 ： |
Candy Ton |
| 【电子邮件】 ： |
yuanyuanton@gmail.com |
| 【联系电话】 ： |
1-631-5599269 |
| 【发布日期】 ： |
2015-1-26 |
| 【详细说明】 ： |
Product Overview
Recombinant Human Stefin-A produced in E.Coli encodes full length amino acids and has a molecular mass of 37 kDa.
Description
Stefin A is the intracellular inhibitor of cysteine proteinase cathepsin B (CatB) and belongs to family 1 of the cystatin superfamily of inhibitor proteins. It has been proposed that extracellular CatB together with other classes of proteinases are all subjected to a cascade-like manner of activation. CatB and its inhibitor Stefin A are involved in degradation of extracellular matrix proteins during tissue remodeling. Stefin A has been reported to be found in high concentrations in epithelial cells, polymorphonuclear leukocytes and lymphoid tissue.
Source
Escherichia Coli.
Formulation
Recombinant Human Stefin A protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Application and suggested dilutions
ELISA, Inhibition Assays, Western Blotting.
Characterization
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 37 kDa. |
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English
