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| 【主 题】 ： |
Recombinant Human Cystatin B (Stefin B), His-tagged |
| 【联系人名】 ： |
Candy Ton |
| 【电子邮件】 ： |
yuanyuanton@gmail.com |
| 【联系电话】 ： |
1-631-5599269 |
| 【发布日期】 ： |
2015-1-26 |
| 【详细说明】 ： |
Product Overview
Recombinant CSTB, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques (118 aa, 13kDa).
Description
CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to form a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes. In cells, CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus.
Source
E.coli.
Formulation
Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 50 mM NaCl.
Molecular Weight
13 kDa (118 aa).
Purity
> 95% by SDS – PAGE.
Concentration
1 mg/ml (determined by Bradford assay).
Endotoxin Level
< 1.0 EU per 1 μg of protein (determined by LAL method). |
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