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| 【主 题】 ： |
Recombinant Human Cathepsin A, His-tagged |
| 【联系人名】 ： |
Candy Ton |
| 【电子邮件】 ： |
yuanyuanton@gmail.com |
| 【联系电话】 ： |
1-631-5599269 |
| 【发布日期】 ： |
2015-1-26 |
| 【详细说明】 ： |
Product Overview
Recombinant Human CTSA protein (Met 1- Tyr 480), fused with a his tag at the C-terminus, was expressed in Human Cells.
Description
Cathepsin A / lyososomal carboxypeptidase A, is a lysosomal serine protease with structural homology to yeast carboxypeptidase Y. The enzyme is synthesized as a 54kDa precursor/zymogen and processed into a catalytically active 32 and 20kDa two-chain form. linked by disulfide bonds. In addition to its carboxypeptidase activities at acidic pH, cathepsin A also serves as a multicatalytic enzyme with deamidase and esterase activities at neutral pH. Also identified as a lyososomal protective protein distinct from its catalytic function., cathepsin A associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers, and provides a protective role for stability and activity.
Source
Human Cells.
Molecular Mass
The secreted recombinant human CTSA existing as a single-chain form consists of 463 amino acids and has a predicted molecular mass of 53 KDa as estimated by SDS-PAGE under reducing conditions.
Predicted N Terminal
Ala 29. |
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