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| 【主 题】 ： |
Recombinant Mouse Cathepsin A, His-tagged |
| 【联系人名】 ： |
Candy Ton |
| 【电子邮件】 ： |
yuanyuanton@gmail.com |
| 【联系电话】 ： |
1-631-5599269 |
| 【发布日期】 ： |
2015-1-26 |
| 【详细说明】 ： |
Product Overview
Recombinant Mouse Ctsa protein (Met 1-Tyr 474), fused with a his tag at the C-terminus, was expressed in Human Cells.
Description
Mouse cathepsin A / lyososomal carboxypeptidase A, is a lysosomal serine protease with structural homology to yeast carboxypeptidase Y. This enzyme is synthesized as a 54kDa precursor/zymogen and is processed into a catalytically active 32 and 20kDa two-chain form. linked by disulfide bonds. In addition to its carboxypeptidase activities at acidic pH, cathepsin A also serves as a multicatalytic enzyme with deamidase and esterase activities at neutral pH. Also identified as a lyososomal protective protein distinct from its catalytic function., cathepsin A associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers, and provides a protective role for stability and activity.
Source
Human Cells.
Molecular Mass
The secreted recombinant mouse CTSA consists of 462 amino acids and has a calculated molecular mass of 52.8 kDa as estimated in SDS-PAGE under reducing conditions.
Predicted N Terminal
Ala 24.
Purity
> 96 % as determined by SDS-PAGE. |
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